| 引用本文: | 张璐,方玲,余欢欢,张国亮,侯晓虹,李振皓.基于UPLC-Q-TOF-MS的不同月份铁皮石斛次生代谢物动态变化规律研究[J].中国现代应用药学,2024,41(14):14-13. |
| Zhang Lu,Fang Ling,Yu Huanhuan,Zhang Guoliang,Hou Xiaohong,Li Zhenhao.Dynamic variation patterns of secondary metabolites in Dendrobium officinale of different months based on UPLC-Q-TOF-MS[J].Chin J Mod Appl Pharm(中国现代应用药学),2024,41(14):14-13. |
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| 摘要: |
| 目的 探究铁皮石斛中次生代谢产物在不同月份的变化规律,为铁皮石斛资源的精细化开发提供依据。方法 利用超高效液相色谱-飞行时间质谱联用(UPLC-Q-TOF-MS)结合分子网络技术快速鉴定铁皮石斛中的次生代谢产物,并对连续12个月的铁皮石斛样品中酚类、黄酮等化合物的相对含量进行比较分析。结果 共鉴定出9类56种次生代谢产物,其中酚类、黄酮及萜类的相对含量均在11月达到最高。结论 11月可作为铁皮石斛的最佳采收期,该研究有助于铁皮石斛资源的精准利用。 |
| 关键词: 铁皮石斛 次生代谢产物 动态变化规律 超高效液相色谱-四极杆飞行时间质谱 |
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| Dynamic variation patterns of secondary metabolites in Dendrobium officinale of different months based on UPLC-Q-TOF-MS |
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Zhang Lu1, Fang Ling2, Yu Huanhuan2, Zhang Guoliang2, Hou Xiaohong1, Li Zhenhao2
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1.Shenyang Pharmaceutical University;2.Zhejiang ShouXianGu Botanical Drug Institute Co., Ltd.
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| Abstract: |
| OBJECTIVE To explore dynamic variation patterns of secondary metabolites in Dendrobium officinale at different months, and to provide data for the precision utilization of Dendrobium officinale resources. METHODS Secondary metabolites of Dendrobium officinale were rapidly identified using UPLC-QTOF-MS combined with molecular networking, and the relative contents of phenols, flavonoids, and other compounds of Dendrobium officinale for 12 consecutive months were analyzed. RESULTS A total of 9 categories and 56 types of secondary metabolites were identified, and phenols, flavones, and terpenoids reached highest relative contents in November. CONCLUSION November can be regarded as the potential optimal harvesting time for Dendrobium officinale, and this study is conducive to maximizing the utilization of Dendrobium officinale resources. |
| Key words: Dendrobium officinale Secondary metabolites Dynamic variation patterns UPLC-QTOF-MS |
