儿童斑秃的药物治疗进展

Research Progress of Drugs in Treating Pediatric Alopecia Areata

关键词:  儿童  斑秃  药物  治疗

Key words:  pediatric  alopecia areata  drugs  treatment

摘要:

斑秃是儿童常见皮肤病,主要表现为圆形或椭圆形脱发斑,严重者可进展为全秃或普秃。斑秃会影响外貌,从而影响患儿的心理健康,故及时控制病情至关重要。外用糖皮质激素仍是治疗儿童斑秃的一线方案,对于外用糖皮质激素治疗无效者或病情进展较快者,可考虑采用其他治疗手段。近年来,Janus激酶抑制剂、生物制剂等给治疗带来了新的希望。

Abstract:

Alopecia areata（AA）is characterized by patchy hair loss，severe hair loss forms include the complete loss of scalp hair or alopecia totalis（AT）and complete loss of all hair or alopecia universalis（AU）. AA affects the mental health of patients, so it is very important to control the progress of AA. Topical corticosteroids is still the first-line treatment for children with AA, For those who fail to respond to topical corticosteroids or whose disease progresses rapidly, other therapeutic means may be considered. In recent years, Janus kinase inhibitors, biological agents offer new hope for the treatment.