氧化铁纳米粒在肿瘤诊断与治疗方面的应用

Application of iron oxide nanoparticles in tumor diagnosis and treatment

关键词:  氧化铁  纳米粒,肿瘤  肿瘤诊断  肿瘤治疗

Key words:  Iron oxide  nanoparticles  tumor  tumor diagnosis  tumor treatment

摘要:

基于氧化铁纳米粒的可降解性、低细胞毒性、成像性能、光热效应和载体能力等卓越的理化性质,以及其多样化的合成方法,它们在肿瘤诊断与治疗中的应用受到了广泛研究。氧化铁纳米粒不仅在核磁共振成像和计算机断层扫描等肿瘤诊断技术中展现出重要的应用价值,还在肿瘤治疗领域,如光热治疗、光动力学治疗及药物治疗中发挥了关键作用。基于这些特性,本文将对氧化铁纳米粒的性质、合成方法及其在肿瘤诊断与治疗中的应用进行综述,以说明其临床应用的可能性。

Abstract:

Based on the excellent physical and chemical properties such as degradability, low cytotoxicity, imaging performance, photothermal effect and carrier ability of iron oxide nanoparticles, as well as their diverse synthesis methods, their application in tumor diagnosis and treatment has been widely studied. Iron oxide nanoparticles not only show important application value in tumor diagnostic techniques such as nuclear magnetic resonance imaging and computed tomography, but also play a key role in the field of tumor therapy, such as photothermal therapy, photodynamic therapy and drug therapy. Based on these characteristics, this paper will review the properties, synthesis methods and applications in tumor diagnosis and treatment of iron oxide nanoparticles to illustrate the possibility of their clinical application.