口服质子泵抑制剂的多准则量化评价实践

Multicriteria Quantitative Evaluation Practice of Oral Proton Pump Inhibitors

关键词:  质子泵抑制剂  医院药学  量化评价  药品遴选

Key words:  proton pump inhibitor  hospital pharmacy  quantitative evaluation  drug selection

摘要:

目的 通过对河北省人民医院所有口服质子泵抑制剂进行多准则量化评价，为医院药事管理与药物治疗学委员会进行药品目录调整、临床应用评价等药事管理工作提供依据。方法 建立包含必要性、有效性、安全性、经济性、国家医保、国家基本药物、一致性评价、贮藏条件、药品有效期、全球使用情况、企业状况11个准则的“药品量化评分表”，并由信息药师对6个品种共10个品规的口服质子泵抑制剂进行量化评价。结果 10个口服质子泵抑制剂得分在52~78分，奥美拉唑得分最高，艾普拉唑得分最低，差异主要表现在必要性、经济性等方面。结论 对药品进行的多准则量化评价为药事管理与药物治疗学委员会提供了较为全面的证据，通过对评分与用量进行分析可明确管理重点，有推广应用的价值。

Abstract:

OBJECTIVE To provide the selection basis for pharmaceutical management such as drug catalog adjustment and clinical application evaluation by multi-criteria quantitative evaluation of oral proton pump inhibitors in Hebei General Hospital. METHODS To establish a “Drug Quantitative Scoring Table” which based on 11 criterias: necessity, effectiveness, safety, economy, national medical insurance, national essential medicines, consistency evaluation, storage conditions, drug expiration dates, global usage, enterprise status. Ten oral proton pump inhibitors of 6 varieties were quantitatively evaluated by the information pharmacist. RESULTS Ten oral proton pump inhibitors scored between 52-78, omeprazole had the highest score and ilaprazole had the lowest score. The differences were mainly in the aspects of necessity and economy. CONCLUSION The multi-criteria quantitative evaluation of drugs provides comprehensive evidence for the drug and therapeutics committee. The management focus can be clarified by analyzing the score and dosage, which has the value of promotion and application.