珍珠菜属植物的化学成分及药理作用研究进展

Progress Research of Chemical Constituents and Pharmacological Activities of Lysimachia

关键词:  珍珠菜属  黄酮类  三萜类  抗肿瘤  抗菌  抗氧化

Key words:  Lysimachia  flavonoids  triterpenes  antitumor  antimicrobial  antioxygen

摘要:

珍珠菜属(Lysimachia L.)植物在我国分布广泛、资源丰富，其中多种植物在民间药用，过路黄(L. christinae)的干燥全草为常用中药金钱草的基源植物。本属植物中含有大量的黄酮类、三萜类、挥发油等化学成分；现代药理学研究表明，该属植物提取物或某些成分在抗肿瘤、抗菌、抗氧化等方面显示了较好的生物活性。本文对近年来国内外报道的珍珠菜属植物化学成分及药理作用研究进行综述，为进一步研究开发该属植物资源提供依据。

Abstract:

The plants of genus Lysimachia are widespread in China and abundant in resource. Many of them have been used as folk-medicines in China for a long time, e.g., the dry herb of L.chridtinae Hance is the original source of Lysimachiae Herba, a frequently used traditional Chinese medicine. The plants of this genus contain a great deal of flavonoids, triterpenes, volatile oil, and so on, and the extracts or some compounds from the plants of the genus exhibited significant biological activities in modern pharmacological researches such as antitumor, antimicrobial, and antioxygen effects. This paper reviewed the research progress on the chemical constituents and pharmacological activities of the plants in the title genus reported in domestic and overseas literature in recent years and provided a reference for further studying and developing this plant resource.