| 引用本文: | 张丹，颜学伟，曹纬国，王刚，刘伟，王永丽.重庆产厚朴不同部位厚朴酚与和厚朴酚分布规律的研究[J].中国现代应用药学,2012,29(7):614-617. |
| ZHANG Dan, YAN Xuewei, CAO Weiguo, WANG Gang, LIU Wei, WANG Yongli.Research on the Distribution of Magnolol and Honokiol in Different Parts of Magnolia Officinalis Rehd.et Wils. from Chongqing[J].Chin J Mod Appl Pharm(中国现代应用药学),2012,29(7):614-617. |
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| 摘要: |
| 目的 研究厚朴不同部位厚朴酚与和厚朴酚的分布规律，为进一步开发利用厚朴资源并对其进行质量控制提供科学依据。方法 采用HPLC测定厚朴不同部位中厚朴酚与和厚朴酚的含量。结果 厚朴根皮、干皮、枝皮和厚朴叶中厚朴酚与和厚朴酚的总含量分别约为：8.22%，2.30%，2.07%和0.43%，厚朴各部位中厚朴酚与和厚朴酚的总含量差异具有统计学意义(P<0.05)。结论 厚朴不同部位中厚朴酚与和厚朴酚的含量差异较大，其质量控制有待深入研究，厚朴不同部位在临床用药时应有所区别，另外厚朴叶资源具有较大的开发价值。 |
| 关键词: 厚朴 厚朴酚 和厚朴酚 高效液相色谱法 |
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| 基金项目:重庆市渝中区科技创新项目(20100208)；重庆市九龙坡区科技项目(2011-62-1) |
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| Research on the Distribution of Magnolol and Honokiol in Different Parts of Magnolia Officinalis Rehd.et Wils. from Chongqing |
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ZHANG Dan, YAN Xuewei, CAO Weiguo, WANG Gang, LIU Wei, WANG Yongli1,2,3
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1.Chongqing Medical University, a.Traditional Chinese Medicine College;2.b.The Lab of Traditional Chinese Medicine Sciences;3.c.Traditional Chinese Medicine Experimental Teaching Center, Chongqing 400016, China
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| Abstract: |
| OBJECTIVE To study the distribution pattern of magnolol and honokiol in different parts of Magnolia officinalis Rehd. et Wils. from Chongqing, so as to provide a scientific basis for further development and utilization of its resources and quality control. METHODS The content of magnolol and honokiol in the different parts of Magnolia officinalis Rehd.et Wils. was determined by HPLC. RESULTS The total content of magnolol and honokiol in root bark, trunk bark, branch bark and leaf of Magnolia officinalis Rehd. et Wils. was different as 8.22%, 2.30%, 2.07% and 0.43%. The content of magnolol and honokiol in the different parts of Magnolia officinalis Rehd.et Wils. showed distinct variability. CONCLUSION The content of magnolol and honokiol in the different parts of Magnolia officinalis Rehd.et Wils. was different significantly. The quality control of magnolia bark should be lucubrated, and the clinical medication of the different parts should be distinguished. The leaf resources of Magnolia officinalis Rehd.et Wils. possess exploitation potentials. |
| Key words: Magnolia officinalis Rehd.et Wils. magnolol honokiol HPLC |
