醒脾养儿颗粒结合心理行为疗法治疗小儿原发性夜间遗尿症的临床研究

Clinical Observation on Treatment of Primary Nocturnal Enuresis with Xingpiyang’er Particles Combined with Psychological Behavior Therapy in Children

关键词:  小儿原发性夜间遗尿症  醒脾养儿颗粒  心理行为疗法

Key words:  primary nocturnal enuresis  Xingpiyang’er particles  psychological behavior therapy

摘要:

目的 观察苗药醒脾养儿颗粒结合心理行为疗法治疗小儿原发性夜间遗尿症的临床疗效及复发率。方法 157例确诊为原发性单一症状性夜间遗尿症的患儿，在家长和患儿同意进行2个月的治疗并坚持随访情况下，将其随机分为2组：①单纯心理行为治疗组70例；②联合治疗组87例，醒脾养儿颗粒口服结合心理行为疗法治疗。家长和患儿决定暂不治疗或延期治疗的64例患儿归为对照组，并定期随访。对3组患儿2个月治疗结束时，和停止治疗3个月后遗尿症的缓解情况进行比较分析。结果 联合治疗组总有效率为72.09%，单纯心理行为治疗组总有效率为46.37%，两组比较差异有统计学意义，联合治疗组复发率为12.79%，明显低于单纯心理行为治疗组的26.47%，两者比较差异有统计学意义。结论 醒脾养儿颗粒结合心理行为疗法治疗小儿原发性遗尿症疗效显著且复发率低，临床用药简单，无明显不良反应，易被广大遗尿症患儿接受，值得临床推广应用。

Abstract:

OBJECTIVE To observe the clinical efficacy and the recurrence rate of combination Xingpiyang’er particles and psychological behavior therapy for treating the primary nocturnal enuresis (PNE) in children. METHODS If the parents and children consented to accept the treatment for 2 months and to keep on follow-up, the children diagnosed as primary noctur- nal enuresis were randomized into two groups: 70 children were in physio-psychological treatment group alone; 87 children were in combined treatment group who were treated with combination Xingpiyang’er particles orally and psychology behavior therapy. If the parents and children did not accept treatment, they were enrolled into the control group and were followed-up. Then, the curative effects of the two groups were compared statistically after the 2 months treatment and compared again 3 months later. RESULTS The total effective rate of the combined group was 72.09%, and the physio-psychological treatment group were 46.37%, there was significant difference(P<0.05); the recurrence rate in combined group was 12.79% which was significantly lower than the physio-psychological treatment group (26.47%, P<0.05). CONCLUSION The combination of Xingpiyang’er particles and psychology behavior therapy might have better curative effect and lower relapse rate than that the single usage, no obvious adverse reaction is observed. It is easy to be accepted by children and more suitable for widespread use to treat PNE.