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引用本文:杨毅,金祖汉,毛培江,金捷,黄晶晶,杨明华.黄秋葵提取物抗疲劳的实验研究[J].中国现代应用药学,2012,29(12):1090-1094.
YANG Yi,,JIN Zuhan,MAO Peijiang,JIN Jie,HUANG Jingjing,YANG Minghua.Study on Anti-fatigue Effects of Okra Extracts[J].Chin J Mod Appl Pharm(中国现代应用药学),2012,29(12):1090-1094.
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黄秋葵提取物抗疲劳的实验研究
杨毅, 金祖汉, 毛培江, 金捷, 黄晶晶, 杨明华
浙江省中药研究所,杭州 310023
摘要:
目的 观察黄秋葵水提物对实验动物的抗疲劳作用,探讨黄秋葵水提物抗疲劳作用的机制。方法 以观察小鼠负重力竭游泳时间探讨黄秋葵提取物抗疲劳作用;测定小鼠游泳前后血清尿素的变化、小鼠肝糖原含量、小鼠血乳酸等探讨抗疲劳机制。结果 黄秋葵提取物能明显延长小鼠负重游泳时(P<0.05),减少小鼠血清尿素产生(P<0.01),减少小鼠血乳酸含量(P<0.05),对小鼠肝糖原含量无明显影响。结论 黄秋葵提取物具有良好的抗疲劳作用。该作用可能与提高小鼠代谢能力和增强应激能力有关。
关键词:  黄秋葵  抗疲劳  小鼠
DOI:
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基金项目:浙江省科技厅重大科技专项(2010C12013)
Study on Anti-fatigue Effects of Okra Extracts
YANG Yi,, JIN Zuhan, MAO Peijiang, JIN Jie, HUANG Jingjing, YANG Minghua
Zhejiang Research Institue of Traditional Chinese Medcine, Hangzhou 310023, China
Abstract:
OBJECTIVE To observe the water extracts from okra on anti-fatigue effects in mice, to explore anti-fatigue effect mechanism of water extracts from okra. METHODS To discuss the anti-fatigue effects of water extracts from okra through weight loading swimming test on mice; to explore the anti-fatigue mechanism by analysis of serum urea changes, hepatic glycogen and serum lactic acid before and after swimming. RESULTS Compared with the control group, the swimming time was increased significantly(P<0.05) in okra extracts groups, and the production of serum urea and serum lactic acid was decreased(P<0.05 and P<0.01), while there was no significant difference of muscle glycogen. CONCLUSION The anti-fatigue effects of okra extracts was obvious. It may be related to the improved metabolic capacity and enhanced ability stress of mice.
Key words:  okra  anti-fatigue  mice
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