| 引用本文: | 周虹云,吴长顺,程存归.野菊花化学成分研究[J].中国现代应用药学,2013,30(1):31-35. |
| ZHOU Hongyun,WU Changshun,CHENG Cungui.Studies on Chemical Constituents from Chrysanthemum Indicum L.[J].Chin J Mod Appl Pharm(中国现代应用药学),2013,30(1):31-35. |
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| 摘要: |
| 目的 研究野菊花的化学成分。方法 用80%乙醇提取野菊花化学成分，通过硅胶反复柱层析、纯化，用各种波谱数据分析鉴定化合物的结构。结果 从野菊花头状花序中的乙酸乙酯提取物、氯仿提取物及正丁醇提取物中分离得到11个化合物，分别鉴定为香叶木素(Ⅰ)，木犀草素(Ⅱ)，木犀草素-7-O-β-D-葡萄糖苷(Ⅲ)，芹菜素(Ⅳ)，β-谷甾醇(Ⅴ)，山奈酚(Ⅵ)，大黄酚(Ⅶ)，蒙花苷(Ⅷ)，金合欢素(Ⅸ)，金合欢素-7-O-(6″-O-乙酰基)-β-D-葡萄糖苷(Ⅹ)和金合欢素-7-Ｏ-β-Ｄ-芦丁糖苷(Ⅺ)。结论 其中化合物Ⅹ~Ⅺ为首次从野菊花中分离得到。 |
| 关键词: 菊花 化学成分 结构鉴定 |
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| Studies on Chemical Constituents from Chrysanthemum Indicum L. |
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ZHOU Hongyun1, WU Changshun2, CHENG Cungui3
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1.Department of Pharmacy, Zhejiang Jinhua Munucipal Central Hospital, Jinhua 321000, China;2.Zhejiang Normal University, Chuyang Honors College, Jinhua 321004, China;3.Zhejiang Normal University, College of Chemistry and Life Science, Jinhua 321004, China
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| Abstract: |
| OBJECTIVE To study the chemical constituents in Chrysanthemum indicum L. METHODS Extract chemical continents from Chrysanthemum indicum L. by using 80% alcohol and silica gel column chromatography methods. The structure of the isolated compounds were identified by physicochemical identification and spectral analysis methods, such as UV, FTIR, EI-MS, ESI-MS, 1H-NMR, 13C-NMR, and so on. RESULTS Eleven compounds were isolated from the ethyl acetate extracts, chloroform extracts and the n-butanol extracts of Chrysanthemum indicum L. They were chrysoeriol(Ⅰ) , luteolin(Ⅱ) , luteolin-7-O-β-D-glucopyranoside (Ⅲ), apigenin(Ⅳ), β-sitosterol(Ⅴ), kaempferol(Ⅵ), chrysophanol(Ⅶ), linarin(Ⅷ), acacetin(Ⅸ), acacetin 7-O-(6″-O-acetyl)-β-D-glucopyranoside(Ⅹ) and acacetin-7-O-β-D-rutinoside(Ⅺ), respectively. CONCLUSION Among them, compounds Ⅹ and Ⅺ were isolated from Chrysanthemum indicum L. for the first time. |
| Key words: Chrysanthemum indicum L. chemical constituents structure identification |
