综合性医院3种肠道清洁剂的药物利用调查

Drug Utilization Study of Three Intestinal Cleaning Agents in a General Hospital

关键词:  肠道清洁剂  药物利用  药物经济学  最小成本分析法  每日限定剂量

Key words:  intestinal cleaning agents  drug utilization  pharmacoeconomics  cost minimization analysis  defined daily dose

摘要:

目的 了解市售3种聚乙二醇电解质型肠道清洁剂的药物利用情况。方法 利用浙江大学医学院附属第二医院HIS系统，调查了3种肠道清洁剂的临床医嘱或处方，进行数据挖掘。计算用药频度、日用金额等药物利用参数，应用最小成本分析法进行药物经济学比较。结果 3种肠道清洁剂临床使用疗效确切，患者服用后无明显的不耐受。恒康正清的用药频度最高，是舒泰清与和爽用药频度的2倍。和爽的给药最为方便，在配制灌洗液时无“漏掉小包”的缺陷，且日用金额最低。结论 3种肠道清洁剂中和爽最具有药物经济学价值。

Abstract:

OBJECTIVE To know the utilization status of three intestinal cleaning agents in clinical practice. METHODS Retrospective analysis of prescriptions with three intestinal cleaning agents was performed from hospital information system in our hospital. Data mining was conducted. Parameters of drug utilization study were calculated and pharmacoeconomic indices were compared by using cost minimization analysis. RESULTS The three drugs were effective without obvious intolerance in clinical use. The DDDs value of product Hengkang Zhengqing ranked first, twice the value of either Shutai Qing or Heshuang. Product Heshuang had the lowest risk of administration errors due to its “all in one” characteristics and also it had the lowest daily expenditure. CONCLUSION Product Heshuang is the most pharmacoeconomic intestinal cleaning agent.