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引用本文:刘桂花,薛桂蓬,邢建国,谢婷.复方苏润江滴丸提取工艺研究[J].中国现代应用药学,2013,30(4):399-403.
LIU Guihua,XUE Guipeng,XING Jianguo,XIE Ting.Study on Extraction Process of Compound Surunjiang Dripping Pill[J].Chin J Mod Appl Pharm(中国现代应用药学),2013,30(4):399-403.
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复方苏润江滴丸提取工艺研究
刘桂花1, 薛桂蓬1, 邢建国1, 谢婷2
1.新疆维吾尔自治区药物研究所,乌鲁木齐 830004;2.石河子大学药学院,新疆 石河子 832002
摘要:
目的 优选复方苏润江滴丸提取工艺。方法 采用正交试验设计,分别以秋水仙碱含量、芦荟苷含量和浸膏得率为指标,优选秋水仙等3味药材的乙醇提取工艺;以总多糖含量和浸膏得率为指标,优选盒果藤根皮等4味药材的水提取工艺。结果 3味药材的最佳提取工艺为8倍量70%乙醇,提取2次,每次1.0 h;4味药材的最佳提取工艺为10倍量水,提取3次,每次1.5 h。结论 优选的提取工艺稳定、可行。
关键词:  复方苏润江滴丸  秋水仙碱  芦荟苷  总多糖  正交试验  提取工艺
DOI:
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基金项目:新疆维吾尔自治区重大科技专项(201130105-3)
Study on Extraction Process of Compound Surunjiang Dripping Pill
LIU Guihua1, XUE Guipeng1, XING Jianguo1, XIE Ting2
1.Xinjiang Institute of Meteria Medica, Urumchi 830004, China;2.Pharmacy Department of Shihezi University, Shihezi 832002, China
Abstract:
OBJECTIVE To optimize the extraction process of Compound Surunjiang Dripping Pill. METHODS Orthogonal experimental design was used for optimization, the extract yield, the content of colchicine and aloin were taken as the indexes in extracting process of three herb medicines; the extract yield and the content of polysaccharide were taken as the indexes in extracting process of four herb medicines. RESULTS The optimum extraction progress was as follows: three herb medicines were extracted 2 times for 1 h with 8 times amount of 70% alcohol; four herb medicines were extracted 3 times for 1.5 h with 10 times amount of water. CONCLUSION The optimum extraction process is stable and feasible.
Key words:  Compound Surunjiang Dripping Pill  colchicine  aloin  polysaccharide  orthogonal test  extraction technique
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