| 引用本文: | 陈青华,胡静洁,田自有.注射用多索茶碱与注射用阿洛西林的配伍稳定性考察[J].中国现代应用药学,2014,31(1):110-112. |
| chenqinghua,hujingjie,tianziyou.Study on the Compatible Stability of DoxofyllineInjection and Azlocillin Injection[J].Chin J Mod Appl Pharm(中国现代应用药学),2014,31(1):110-112. |
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| 摘要: |
| 目的：考察注射用多索茶碱与注射用阿洛西林的配伍稳定性。 方法：观察及测定注射用多索茶碱与注射用阿洛西林在0.9%氯化钠注射液中配伍后于室温条件下放置6h内的外观及PH值,并采用高效液相色谱法测定配伍液的含量。 结果：与配伍后0h比较,配伍液在6h内的外观和含量都没有明显的变化,而PH值有所浮动。 结论：注射用多索茶碱与注射用阿洛西林在0.9%氯化钠注射液中配伍后于室温下放置6h内质量较稳定。 |
| 关键词: 注射用多索茶碱 注射用阿洛西林 配伍 稳定性 高效液相色谱法 |
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| Study on the Compatible Stability of DoxofyllineInjection and Azlocillin Injection |
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chenqinghua,hujingjie,tianziyou
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1.Taizhou Central Hospital;2.Wenzhou Medical College Renji College
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| Abstract: |
| ABSTRACT OBJECTIVE： To study the compatible stability of doxofylline injection and azlocillin injection. METHODS: The changes in appearance and PH value of the mixture of doxofylline injection and azlocillin injection in 0.9% sodium chloride injection within 6 hours at room temperature were observed and detemined,the contect of which determined by HPLC. RESULTS: Compared with the solution at 0h after mixing，no significant changes were found in appearance and content within 6 hours mixing，however，there was a fluctuation in its PH value. CONCLUSION: the mixture of doxophylline and azlocollin in 0.9% Sodium chloride is stable in quality wthinin 6 hours mixing at room temperature。 |
| Key words: Doxofylline injection Azlocillin injection Compatibility Stability HPLC |
