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引用本文:郑造乾,王小军,杨秀丽,陈燕华.头孢西丁钠致过敏性紫癜1例[J].中国现代应用药学,2015,32(1):112-113.
ZHENG Zhaoqian,WANG Xiaojun,YANG Xiuli,CHEN Yanhua.Anaphylactoid purpura induced by cefoxitin sodium:a case report[J].Chin J Mod Appl Pharm(中国现代应用药学),2015,32(1):112-113.
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头孢西丁钠致过敏性紫癜1例
郑造乾1, 王小军1, 杨秀丽1, 陈燕华1
浙江省立同德医院药剂科,杭州 310012
摘要:
1例58岁女性急性扁桃体炎患者应用头孢西丁2.0g,2次/d静滴。在次日静滴后约30min,患者出现腹痛,全身皮肤暗红色皮疹。实验室检查镜下红细胞8-9/HP,隐血 1,尿沉渣红细胞32/μL。诊断为过敏性紫癜。立即停用头孢西丁,给予马来酸氯苯那敏、地塞米松、葡萄糖酸钙、氯雷他定、醋酸泼尼松等治疗,次日暗红色皮疹消退,腹痛消失,镜下红细胞0-3/HP,隐血 -,尿沉渣红细胞5/μL,一周后,患者暗红色皮疹完全消失。
关键词:  头孢西丁钠
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Anaphylactoid purpura induced by cefoxitin sodium:a case report
ZHENG Zhaoqian,WANG Xiaojun,YANG Xiuli,CHEN Yanhua
Abstract:
【】A female patient aged 58 years with acute tonsillitis was treated with cefoxitin 2.0g twice daily.The day after,patient had abdominal pain and dark red rash on whole body skin after intravenous drip cefoxitin about 30 min. Laboratory tests showed the following values:microscopically RBC 8-9 / HP, occult blood 1, urine sediment RBC 32 /μL.Then anaphylactoid purpura is diagnosed. The patient was immediately stoped using cefoxitin, and treated with chlorphenamine maleate,dexamethasone,calcium gluconate, ioratadine and prednisone acetate. The day after,dark red rash fades and abdominal pain disappears.The microscopic RBC 0-3/HP, occult blood -, urine sediment RBC 5 /μL.After a week, patients with dark red skin rashes completely disappear.
Key words:  Cefoxitin  anaphylactoid purpura  adverse reactions
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