引用本文: | 孙胜斌,陈翔宇,高晗,姜国志,李军山,李振江.近红外光谱法快速分析不同厂家炒栀子配方颗粒的质量[J].中国现代应用药学,2015,32(8):960-963. |
| SUN Shengbin,CHEN Xiangyu,GAO Han,JIANG Guozhi,LI Junshan,LI Zhenjiang.Rapid Analysis of the Quality of Formula Granule of Stir-baked Gardeniae Fructus Formula from Different Manufacturers by Near-infrared Spectroscopy[J].Chin J Mod Appl Pharm(中国现代应用药学),2015,32(8):960-963. |
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摘要: |
目的 考察不同厂家炒栀子配方颗粒的质量。方法 利用近红外光谱仪直接对各厂家样品进行积分球漫反射全波长扫描,用马氏距离法分类建模,计算不同厂家配方颗粒间的距离。结果 A、B、C厂家炒栀子配方颗粒间距离均较大,相互间区别明显。结论 不同厂家生产的炒栀子配方颗粒质量相互间有一定差异。 |
关键词: 近红外光谱法 炒栀子 配方颗粒 质量 |
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基金项目:国家中医药管理局中医药科学技术研究专项项目(国中医药科2013ZX07) |
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Rapid Analysis of the Quality of Formula Granule of Stir-baked Gardeniae Fructus Formula from Different Manufacturers by Near-infrared Spectroscopy |
SUN Shengbin1,2, CHEN Xiangyu3, GAO Han1, JIANG Guozhi2, LI Junshan1, LI Zhenjiang1
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1.Shineway Pharmaceutical Group Co., Ltd., Shijiazhuang 051430, China;2.State-local Joint Engineering Laboratory of New Drugs Development Technology for TCM Injection, Shijiazhuang 051430, China;3.Hebei Province Engineering Research Center for TCM Injection, Shijiazhuang 051430, China
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Abstract: |
OBJECTIVE To analyse the quality of formula granule of stir-baked Gardeniae Fructus from different manufacturers. METHODS Integrating sphere diffuse full-wavelength scanning of samples from different manufacturers were measured by near-infrared spectroscopy. Mahalanobis distance was used to categoriz modeling and calculate the distance between different manufacturers. RESULTS The distances of formula granule of stir-baked Gardeniae Fructus formula produced by A, B and C were obviously different. CONCLUSION There are certain diversities of quality of formula granule of stir-baked Gardeniae Fructus from different manufacturers. |
Key words: near-infrared spectroscopy stir-baked Fructus Gardeniae formula granule quality |