| 引用本文: | 刘学娜,柴奇,韩维娜.含硫核苷化合物的研究进展[J].中国现代应用药学,2016,33(2):246-249. |
| LIU Xuena,CHAI Qi,HAN Weina.Research Progress of Nucleoside Sulfur Compounds[J].Chin J Mod Appl Pharm(中国现代应用药学),2016,33(2):246-249. |
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| 摘要: |
| 硫是人体必不可少的常量元素之一，也是药物结构修饰的常用元素。含硫药物有着广泛的生物活性，其中，含硫核苷的衍生物在抗肿瘤、抗病毒、抗菌等方面均具有很高的活性。因此本文对已经上市药物和正在研究开发的含硫核苷类化合物进行综述。 |
| 关键词: 硫 硫代核苷 生物活性 |
| DOI： |
| 分类号: |
| 基金项目:黑龙江省自然科学基金项目(H201404) |
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| Research Progress of Nucleoside Sulfur Compounds |
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LIU Xuena, CHAI Qi, HAN Weina
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College of Pharmacy, Harbin Medical University, Harbin 150081, China
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| Abstract: |
| Sulfur is one of the human body essential macro-elements and the medicinal structural modifications common elements. Sulfur-containing compounds have the remarkable biological activities. Furthermore, thionucleoside derivatives have the high activities in anti-tumor, anti-virus and antibacterial field. Therefore, this paper is going to summarize the medicine which is already on the market and the thionucleoside derivatives which is still in the research and development stage. |
| Key words: sulfur thionucleoside biological activity |
