| 引用本文: | 祝明,陈碧莲,石上梅.中药指纹图谱技术在中国药典2015年版一部中的应用[J].中国现代应用药学,2016,33(5):611-614. |
| ZHU Ming,CHEN Bilian,SHI Shangmei.Application of Fingerprint Technology on Traditional Chinese Medicine in Chinese Pharmacopoeia (2015 Edition) Volume Ⅰ[J].Chin J Mod Appl Pharm(中国现代应用药学),2016,33(5):611-614. |
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| 摘要: |
| 目的 通过对中国药典2015年版一部新增特征图谱或指纹图谱应用介绍，以便更好地理解与执行新版中国药典。方法 介绍中药指纹图谱技术的不同测定方法、不同评价模式与在中药质量标准中的应用，并列举实例说明。结果 特征图谱与指纹图谱技术应用使得中国药典2015年版一部中药质量整体可控性明显增加。结论 特征图谱与指纹图谱技术在中药质量标准中的应用完善了中药复杂体系质量标准研究思路、方法和模式，也是今后中药质量整体可控性的发展趋势。 |
| 关键词: 中国药典2015年版 指纹图谱 特征图谱 中药质量标准 |
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| 基金项目:浙江省自然科学基金资助项目(LQ12H28001) |
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| Application of Fingerprint Technology on Traditional Chinese Medicine in Chinese Pharmacopoeia (2015 Edition) Volume Ⅰ |
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ZHU Ming1, CHEN Bilian1, SHI Shangmei2
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1.Zhejiang Institute for Food and Drug Control, Hangzhou 310052, China;2.Chinese Pharmacopoeia Commission, Beijing 100061, China
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| Abstract: |
| OBJECTIVE To better understand and perform the new version of Chinese Pharmacopoeia, the new applications of characteristic chromatograms or fingerprint are reviewed in Chinese Pharmacopoeia (2015 Edition) Volume Ⅰ. METHODS The different determination methods and different evaluation models of the traditional Chinese medicine(TMC) fingerprint technologies and some applications in the quality standard of TCM were introduced. Meanwhile, some examples were given. RESULTS Because of applications of the characteristic chromatograms and the fingerprint technology, the integrated quality control of TCM was increased in Chinese Pharmacopoeia (2015 Edition) Volume Ⅰ. CONCLUSION the applications of characteristic chromatograms and the fingerprint technologies in the quality standard of TMC have improved the research ideas, methods and models for the quality standard of TCM complex system. And it is also the development trend of the overall quality control of TCM in the future. |
| Key words: Chinese Pharmacopoeia (2015 Edition) fingerprint specific chromatogram quality standard of traditional Chinese medicine |
