市售小通草质量现状调查及评价

Quality Investigation and Evaluation on Traditional Chinese Medicine Stachyuri Medulla Helwingiae Medulla in Market

关键词:  小通草  质量调查  薄层鉴别  基源鉴定  评价

Key words:  Stachyuri Medulla Helwingiae Medulla  quality investigation  TLC  origin identification  evaluation

摘要:

目的 调查并分析评价市售小通草药材质量，为调控小通草药材质量奠定基础。方法 依托浙江省各地级市药检机构对各属地市区域内药品生产企业、流通及使用领域进行抽样调查，共收集37批有效样品，以中国药典2015年版为标准，结合薄层鉴别，鉴定样品基源并评价质量。结果 浙江省市售小通草来源复杂，正品以喜马山旌节花或中国旌节花为主，偶见少量青荚叶；伪品均为西南绣球。结论 浙江省市售小通草伪品率较高，质量有待进一步提升，建议完善药典质量标准，如增加薄层鉴别法，加强小通草基源考证及基础研究，规范中药流通市场，以确保其临床用药安全。

Abstract:

OBJECTIVE To investigate and analyze the medicinal materials quality of Stachyuri Medulla Helwingiae Medulla in market, and lay the foundation for the quality control of Stachyuri Medulla Helwingiae Medulla. METHODS Relying on the local prefecture drug testing institutions for sampling survey in local pharmaceutical production enterprises, circulation and use fields. Thirty-seven samples were collected and identified, and the quality of samples were evaluated according to the Chinese Pharmacopoeia(2015) as the standard, combined with TLC. RESULTS the origin of Stachyuri Medulla Helwingiae Medulla was complicated in Zhejiang province, the vast majority of authentic varieties were identified as Stachyurus himalaicus Hook. f. et Thoms.or Stachyurus chinensis Franch., but very little of them were identified as Helwingia japonica (Thunb.) Dietr., all the fakes were Hydrangea davidii Franch.. CONCLUSION the false product rate is high, and the quality still need to be improved in Zhejiang province. The suggestions are as follows: improving the quality standard of pharmacopoeia, regulating, such as the increase in TLC; strengthening the original research and basic study of Medulla stachyuri; regularizing the Chinese medicine market, only in this way can the clinical medication security be ensured.