外科减重手术与药物治疗2型糖尿病伴肥胖患者的药物经济学评价

Pharmacoeconomic Evaluation of Surgical Weight Loss Surgery and Drug Therapy for Type 2 Diabetes Mellitus Accompanied with Obesity Patients

关键词:  决策树分析  Ⅱ型糖尿病伴肥胖  腹腔镜胃旁路减重手术

Key words:  decision tree analysis  T2DM accompanied with obesity  laparoscopic subtractive surgery

摘要:

目的 分析腹腔镜胃旁路减重手术和传统药物治疗2型糖尿病（type Ⅱ diabetes mellitus，T2DM）伴肥胖的经济性。方法 回顾性研究南京鼓楼医院2014年6月-2016年5月因T2DM伴肥胖入院的患者76例，分成2组（A组接受腹腔镜胃旁路减重手术，B组接受药物治疗），用决策树分析2组治疗方案的成本效果。结果 治疗24周，A组和B组的期望成本分别是47 353元和3 838元，成本效果比分别是485.1和40.8；治疗48周，A组和B组的期望成本分别是47 438元和6 588元，成本效果比分别是486和70。结论 从成本效果分析结果来看，药物方法治疗T2DM伴肥胖比手术方法更经济。

Abstract:

OBJECTIVE To analyze the economy of laparoscopic subtractive surgery and traditional drug therapy in the treatment of type 2 diabetes mellitus (T2DM) accompanied with obesity.METHODS A total of 76 patients with T2DM accompanied with obesity from June 2014 to May 2016 in Nanjing Drum Tower Hospital were enrolled in this study (Group A:received laparoscopic subtracted gastric bypass surgery; Group B:received drug therapy). Decision Tree was used to analyze the cost-effective of the two groups.RESULTS The expected cost of group A and group B were 47 353 and 3 838 yuan in 24 weeks respectively, the cost-effectiveness ratios were 485.1 and 40.8 respectively; the expected cost of group A and group B were 47 438 and 6 588 yuan in 48 weeks respectively, the cost-effectiveness ratios were 486 and 70.CONCLUSION From the results of cost-effectiveness analysis, drug treatment of T2DM accompanied with obesity is more economical than surgical methods.