某三甲妇儿专科医院治疗甲状腺功能亢进症处方分析

Prescription Analysis of Hyperthyroidism in a Three-level A-rate Woman and Children Hospital

关键词:  甲状腺功能亢进症  处方  分析

Key words:  hyperthyroidism  prescription  analysis

摘要:

目的 分析广东省妇幼保健院甲状腺功能亢进症（甲亢）处方使用药物情况及妊娠期甲亢的发病情况和趋势，促进临床合理用药。方法 分析笔者所在医院2013—2016年甲亢处方。结果 笔者所在医院甲亢及妊娠期甲亢妇女的人数及比例在2013—2016年逐年增加，妊娠期甲亢患者人数最多的人群是30~39岁女性。治疗甲亢的药物主要为丙硫氧嘧啶，辅助用药包括维生素类、护肝药、升白细胞药以及β受体阻断药。结论 诊断为甲亢的患者在2013—2016年的用药情况基本不变，治疗药物主要为丙硫氧嘧啶；妊娠期甲亢患者使用丙硫氧嘧啶+复合维生素B为治疗方案的人数逐年增加，是使用人数最多的治疗方案；甲亢合并肝功能异常的患者主要使用丙硫氧嘧啶+复合维生素B+普萘洛尔+葡醛内酯+辅酶Q10的五联治疗方案，弥漫性甲状腺肿合并甲亢的患者主要使用丙硫氧嘧啶+复合维生素B+普萘洛尔的方案。

Abstract:

OBJECTIVE To analyze the prescription of hyperthyroidism, the tendency of hyperthyroidism and the incidence of hyperthyroidism in pregnancy in Guangdong Women and Children Hospital. And to promote using drug rationally in hospital. METHODS Prescriptions for hyperthyroidism from 2013 to 2016 were analyzed. RESULTS The number of the patients with hyperthyroidism and the number of the pregnant patients with hyperthyroidism and its proportion were increased year by year form 2013 to 2016. The highest number of pregnant patients with hyperthyroidism were women aged from 30 to 39. The drugs to treat hyperthyroidism were mainly propylthiouracil, adjuvant drugs include vitamins, protection liver drugs, leukocyte elevating drugs and β-receptor antagonists. CONCLUSION The situation of medication of the patients diagnosed with hyperthyroidism are basically unchanged from 2013 to 2016, and the therapeutic drug is mainly propylthiouracil. Most pregnant women with hyperthyroidism are mainly treated with propylthiouracil + multivitamin B, and the proportion of the patient is increased year by year. The patients with hyperthyroidism combined with abnormal liver function are mainly treated with propylthiouracill + multivitamin B + propranolol + glucurolactone + coenzyme Q10. The patients with diffuse goiter combined with hyperthyroidism are mainly used in the therapeutic regimen of propyl thiouracil + multivitamin B + propranolol.