疑似利奈唑胺引发肝功能损伤患者的药学监护

Pharmaceutical Care of Liver Function Injury in the Suspicion of Linezolid-induced within a Patient

关键词:  利奈唑胺  肝功能损伤  药学监护  临床药师

Key words:  linezolid  liver function injury  pharmaceutical care  clinical pharmacist

摘要:

目的 探讨临床药师参与1例疑似利奈唑胺引发肝功能损伤患者的药学监护。方法 针对肺部感染患者在使用利柰唑胺过程中出现肝功能损伤的具体病例，临床药师从原发疾病、肝功能变化、合并用药等因素推断利奈唑胺是肝功能损伤的可能原因，并适时提出干预建议。结果 临床药师对患者肝功能损伤的原因进行了及时和准确的分析，医师采纳了临床药师的建议，患者病情得到了控制。结论 临床药师主动参与患者用药过程，给予医师相应的建议，可以确保患者的用药安全有效。

Abstract:

OBJECTIVE To discuss pharmaceutical care of liver function injury in the suspicion of linezolid-induced with clinical pharmacist's participation. METHODS The use of linezolid maybe a possible cause of liver injury through analyzing primary disease, changes in liver function, combined medications and other factors by clinical pharmacist, who also promptly put forward intervention recommendations, in a pulmonary infection case who suffered liver function impairment during use of linezolid. RESULTS A timely and accurate analyse of the causes with liver function injury was carried out by clinical pharmacists, whose recommendations were adopted by clinicians, thus, the patient's condition had been controlled. CONCLUSION Clinical pharmacists actively participate in the treatment processes, give corresponding suggestions to clinical doctors, can ensure the drug safety and effectiveness in patients.