复方木尼孜其颗粒治疗黄褐斑有效性的meta分析

Meta Analysis of Efficacy of Compound Muniziqi Granule in Treatment of Chloasma

关键词:  复方木尼孜其颗粒  黄褐斑  有效性  meta分析

Key words:  Compound Muniziqi granule  chloasma  efficiency  meta analysis

摘要:

目的 系统评价复方木尼孜其颗粒治疗黄褐斑的有效性，为临床提供循证依据。方法 计算机检索中国期刊全文数据库、中国知网（CNKI）、维普数据库（VIP）、万方数据库、EMbase、PubMed、Cochrane图书馆，收集复方木尼孜其颗粒与维生素C加维生素E治疗黄褐斑有效性的随机对照试验。采用RevMan5.3软件对入选试验进行meta分析。结果 共纳入6个随机对照试验，包括578例患者，meta分析结果显示，复方木尼孜其颗粒组治疗黄褐斑的有效率明显高于维生素C加维生素E治疗组。结论 复方木尼孜其颗粒治疗黄褐斑有效性较好。

Abstract:

OBJECTIVE To evaluate the efficacy of Compound Muniziqi granule in the treatment of chloasma, and provide evidence-based reference for clinical treatment. METHODS CJFD, CNKI, VIP, Wanfang, EMbase, PubMed, and Cochrane library database were researched. The randomized controlled trials about Compound Muniziqi granule versus vitamin C plus vitamin E in the treatment of chloasma were collected. Meta analysis was performed on the selected experiment by using RevMan 5.3 software. RESULTS A total of 6 randomized controlled trials invoving 578 patients were included. The results of meta analysis indicated that the efficacy of Compound Muniziqi granule in the treatment of chloasma was significantly higher than that of vitamin C plus vitamin E group. CONCLUSION Compound Muniziqi granule is effective in the treatment of chloasma.