PIVAS细胞毒性药物调配及输注质量安全探讨

Study on Cytotoxic Drugs Dispensing and Safety of Infusion in PIVAS

关键词:  静脉用药调配中心  细胞毒性药物  防护措施  稳定性

Key words:  pharmacy intravenous admixture service (PIVAS)  cytotoxic drugs  preventive measure  stability

摘要:

目的 探讨细胞毒性药物集中调配的方法及注意事项，降低医务人员的潜在身体损害。方法 以药物说明书和相关药学专业资料为基础，分析出细胞毒性药物最适宜的调配方法，明确溶媒、溶媒量、药物输注滴速、用药时限及输注注意事项等。结果 明确各类细胞毒性药物调配方法、使用注意事项、用药潜在风险，严格按照输液流程操作，确保用药安全。结论 规范的细胞毒性药物调配方法及操作是药物使用安全、降低医务人员意外损害的重要举措。

Abstract:

OBJECTIVE To explore the methods and precautions for the concentrated deployment of cytotoxic drugs and reduce the potential physical damage to medical personnel. METHODS Based on the drug specification and relevant pharmacy data, the most suitable method for the preparation of cytotoxic drugs was analyzed, and the solvent, the amount of drug, the rate of drug infusion, the time limit for drug administration, and the precautions for infusion were determined. RESULTS The methods for the preparation of various cytotoxic drugs, precautions for use, and potential risks of drug use were clarified, and the procedures were strictly followed to ensure the safety of the drug. CONCLUSION The normative method and operation of cytotoxic drug deployment are important measures for the safe use of drugs and the reduction of accidental injuries of medical personnel.