大蓟、小蓟功效的考证和现代研究

Textual Research and Modern Study of the Effect of Cirsii Japonici Herba and Cirsii Herba

关键词:  大蓟  小蓟  功效  本草  成分  药理  中国药典

Key words:  Cirsii Japonici Herba  Cirsii Herba  effect  herbal  component  pharmacology  Chinese Pharmacopoeia

摘要:

目的 考证大蓟、小蓟治疗痈肿疮毒等功效，指导临床应用。方法 查阅历代本草著作对大蓟、小蓟的记载，及其方剂的应用；综述大蓟、小蓟活性成分及药理作用的区别。结果 历代本草一致认为大蓟具有治疗痈肿疮毒的功效，也有治疗相应疾病的方剂；现代研究表明，大蓟、小蓟含有不同的止血及调节血管的活性成分，具有不同的药理作用；小蓟能够治疗皮肤感染性疾病，大蓟则无，与古文献不一致。结论 中国药典称大蓟、小蓟具有相同功效，均能治疗痈肿疮毒是不严谨的。

Abstract:

OBJECTIVE To study the efficacy of Cirsii Japonici Herba and Cirsii Herba in treating carbuncle and sore toxin, and to guide clinical application. METHODS This paper reviewed the records of Cirsii Japonici Herba and Cirsii Herba in the past dynasties and the application of their prescriptions, and the differences of active ingredients and pharmacological effects between Cirsii Japonici Herba and Cirsii Herba was summarized. RESULTS Herbal books of past dynasties agreed that Cirsii Japonici Herba had the efficacy of treating carbuncle, sore and poison, as well as prescriptions for the treatment of the disease, Cirsii Japonici Herba and Cirsii herba contained different active components, with different pharmacological effects of hemostasis and regulation of vasoactivity, Cirsii herba could treat infectious skin diseases, and Cirsii Japonici Herba could not, which was not consistent with the ancient literature. CONCLUSION It is not strict that Chinese Pharmacopoeia records that the Cirsii Japonici Herba and Cirsii herba has the same effect, can treat carbuncle sore.