类固醇激素联合腕管切开松解术的疗效观察

Clinical Observation on Steroid Hormone Combined with Carpal Tunnel Decompression Surgery

关键词:  腕管综合征  类固醇激素  手术治疗

Key words:  carpal tunnel syndrome  steroid hormone  surgical treatment

摘要:

目的 初步探究在腕管切开松解术的同时局部注射类固醇激素对疗效的影响。方法 收集浙江大学医学院附属第一医院2015年10月至2017年10月收治并获得随访的122例腕管综合征患者，根据术中应用的类固醇激素进行分组，统计术前一般资料与术后CTS-6量表评分并做回顾性分析。结果 术中局部注射类固醇激素相比未注射组的优良率均不存在显著性差异，而且甲泼尼龙琥珀酸钠与复方倍他米松注射液相比也不存在显著性差异。结论 腕管切开松解术中是否进行神经外膜下注射类固醇激素，在远期症状改善方面未见明显差异，类固醇激素联合手术的应用需要更多的研究。

Abstract:

OBJECTIVE To explore the effect of topical injection of steroid hormone during carpal tunnel decompression surgery. METHODS Collected 122 patients with carpal tunnel syndrome(CTS) who were admitted and followed up from October 2015 to October 2017 in the First Affiliated Hospital, College of Medicine, Zhejiang University, were grouped according to the intraoperative steroid hormones. The general preoperative data and postoperative CTS-6 scale scores were collected and analyzed retrospectively. RESULTS There was no statistically significant difference in the excellent and good rates of intraoperative topical injection of steroid hormone groups compared with the non-injection group, and there was no statistically significant difference between methylprednisolone sodium succinate group and compound betamethasone group. CONCLUSION There is no statistically significant difference in the long-term improvement of symptoms in the application of topical steroid hormone injection during carpal tunnel decompression. The application of steroid hormone combined with surgery needs more research.