| 摘要: |
| 目的 探讨注射用丹参（冻干）临床应用的药物相关问题（drug-related problems，DRPs）。方法 通过住院系统电子病历平台，选取蚌埠市第三人民医院2016年1月-2017年9月出院患者中所有使用注射用丹参（冻干）的相关病例，采用国际通用的西班牙DRPs研究方法Granada-Ⅱ分类法，对住院患者注射用丹参（冻干）用药必要性、有效性及安全性进行研究。结果 397份注射用丹参（冻干）病例均发生了DRPs，累计发生1 019药次DRPs，包括413药次DRP5，317药次DRP2，227药次DRP6，62药次DRP4。DRP5主要表现为溶媒量过少，DRP2表现为无适应证用药，DRP6表现为超剂量使用药，DRP4表现为疗程不足。结论 依据DRPs的调查结果，医院应加强注射用丹参（冻干）合理用药干预，提高注射用丹参用药的安全性、必要性及有效性。 |
| 关键词: 注射用丹参(冻干) 药物相关问题 合理用药 |
| DOI：10.13748/j.cnki.issn1007-7693.2019.12.017 |
| 分类号:R969.3 |
| 基金项目:蚌埠市科技发展指导性项目（20160322） |
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| Study for Drug-related Problems of Danshen Freeze-dried Powder for Injection in Clinical Application of Inpatients |
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CHENG Jun
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Department of Pharmaceutical, the Third People's Hospital of Bengbu, Bengbu 233099, China
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| Abstract: |
| OBJECTIVE To study drug-related problems(DRPs) of Danshen freeze-dried powder for injection in clinical application. METHODS Through the inpatient electronic medical records, medical records with Danshen freeze-dried powder for injection from January 2016 to September 2017 in the Third People's Hospital of Bengbu were surveyed statistically. Necessity, safety and effectiveness of Danshen freeze-dried powder for injection clinical application were studied with reference to DRPs of the Spanish Granada-Ⅱ Classification. RESULTS DRPs occurred in all 397 medical records with Danshen freeze-dried powder for injection. Danshen freeze-dried powder for injection accumulated generated 1 019 DRPs, including 413 DRP5, 317 DRP2, 227 DRP6, 62 DRP4. DRP5 mainly showed little solvent content, DRP2 mainly showed no indication, DRP6 mainly showed overdose medication, and DRP2 mainly showed insufficient treatment. CONCLUSION It is necessary for hospitals to develop intervention measure to enhance clinical safety, necessity and effectiveness of Danshen freeze-dried powder for injection in clinical application based on DRPs. |
| Key words: Danshen freeze-dried powder for injection drug-related problems rational drug use |
