中药治疗过敏性哮喘的用药规律分析

Association Rules for Traditional Chinese Medicine Treating Allergic Asthma on Data Mining

关键词:  过敏性哮喘  中药  关联规则

Key words:  allergic asthma  Chinese medicine  association rules

摘要:

目的 探讨中药治疗过敏性哮喘的用药规律。方法 以中药和过敏性哮喘为主题词，搜索中国知网（2008年1月-2018年8月）相关期刊文献，收集文献记载的方剂，建立数据库，进行统计分析。使用Excel 2013、SPSS Clementine 12.0、SPSS Statistics 19.0统计软件对纳入的中药进行关联规则分析。结果 纳入符合标准的期刊文献48篇，共含中药98味，频数共计455次。在纳入的98味中药内，频数≥ 5的中药共30种，频数≥ 10的中药共12种；化痰止咳平喘药、补虚药、解表药在功效分类中最为常见，占比达到74.31%；药性药味中，药味以甘、苦、辛居多，药性以温、平、寒居多；归经分类中，以肺、脾、心经居多。关联规则分析中发现关联强度最高的药对组合为7种。结论 过敏性哮喘的中医治疗用药多以化痰止咳平喘药为主，且多与补虚药联合应用。

Abstract:

OBJECTIVE Explore the rules of traditional Chinese medicine treating Allergic asthma. METHODS Took traditional Chinese medicine and allergic asthma as the main subject, searched the related journal literatures of CNKI(January 2008 to August 2018), collected the prescriptions recorded in literatures, established a database and conducted statistical analysis. Statistical software Excel 2013, SPSS Clementine 12.0 and SPSS Statistics 19.0 were used to conduct association rule analysis for the included traditional Chinese medicine. RESULTS A total of 48 journal literatures were included, containing 98 tastes of traditional Chinese medicine, with a total frequency of 455 times. Among the 98 Chinese medicines, there were 30 Chinese medicines with frequency ≥ 5 and 12 Chinese medicines with frequency ≥ 10. In the efficiency category, antiasthmatic drugs for relieving phlegm and cough, tonic drugs for deficiency and antiseptic drugs were the most common, accounting for 74.31%; Among the medicinal flavors, sweet, bitter and bitter were the most common, while warm, plain and cold were the most common;In the classification of meridians, lung, spleen and heart meridians were the most common. In association rule analysis, the drug combination with the highest association intensity was found to be 7. CONCLUSION Traditional Chinese medicine for the treatment of allergic asthma is mostly used for cough and antiasthmatic drugs, and mostly combined with tonifying deficiency drugs.