血竭及龙血竭化学成分、药理作用研究进展

Advance of the Chemical Components and Pharmacological Effects of Draconis Sanguis and Resina Draconis

关键词:  血竭  龙血竭  化学成分  药理作用  临床应用

Key words:  Draconis Sanguis  Resina draconis  chemical components  pharmacological effect  clinical application

摘要:

目的 血竭为传统名贵中药，龙血竭与血竭化学成分不同，药理作用各有侧重。临床应用时存在两者混用、乱用的现象。本文对两者的研究进展进行文献整理和比较，为临床合理应用提供参考。方法 通过查阅相关文献，对血竭和龙血竭化学成分、药理研究及临床应用进行总结综述。结果 血竭主要成分为血竭素，而龙血竭中主要成分为龙血素A、龙血素B等。血竭对于活血、止血、镇痛、创面愈合等有明显的促进作用，而龙血竭除了具有活血化瘀作用外，在抗真菌、抗炎等方面作用较强。结论 血竭与龙血竭虽均已广泛应用于临床多种疾病的治疗，但两者功效仍有较大差异，建议临床应用予以严格区分。

Abstract:

OBJECTIVE Draconis Sanguis is precious traditional Chinese medicine. Resina draconis and Sanguis Draconis are different in chemical composition, and pharmacological effects. However, the confusion of these two medicines is widespread in clinic. This article compares the research advances of these two medicines to provide reference for clinical application reasonably. METHODS References were reviewed to summarize the chemical composition, pharmacological research and clinical application of Resina draconis and Draconis Sanguis. RESULTS The main component of Draconis Sanguis was hemorrhagic hormone, and loureirin A/B were the main components of Resina draconis. Draconis sanguis had obvious promoting effects on circulation, hemostasis, analgesia, wound healing, etc. The Resina draconis had effects of promoting blood circulation and removing blood stasis, in addition, it had a strong effect on antifungal and anti-inflammatory. CONCLUSION Although both Draconis Sanguis and Resina draconis have been widely used in the treatment of various diseases in clinical practice, the differences in pharmacological effects are obvious. It is necessary to distinguish the two medicines in the clinic.