ICP-MS同时测定化风丹中5种常见金属元素的含量

Simultaneous Determination of the Content of Five Common Metal Elements in Huafeng Dan by ICP-MS

关键词:  微波消解  电感耦合等离子体质谱  化风丹  金属元素

Key words:  microwave digestion  ICP-MS  Huafeng Dan  metal elements

摘要:

目的 建立同时测定化风丹中铜（⁶³Cu）、砷（⁷⁵As）、镉（¹¹⁴Cd）、汞（²⁰²Hg）和铅（²⁰⁸Pb）5种常见金属元素含量的方法。方法 样品用浓硝酸-双氧水（5：1）微波消解后采用微波消解-电感耦合等离子体质谱（ICP-MS）测定5种金属元素的含量，以锗（⁷²Ge）、铟（¹¹⁵In）、铋（²⁰⁹Bi）混合溶液作为内标。结果 该方法对5种金属元素的标准曲线相关系数r>0.999 2，检出限在0.001~0.055 ng·mL^-1，加样回收率在85.67%~114.14%，RSD在1.12%~4.26%。结论 该方法专属性强、快速灵敏，适用于化风丹中5种常见金属元素含量的测定。

Abstract:

OBJECTIVE To establish a method for simultaneous determination of the content of 5 metal elements(⁶³Cu, ⁷⁵As, ¹¹⁴Cd, ²⁰²Hg, ²⁰⁸Pb) in Huafeng Dan. METHODS The samples were digested with concentrated nitric acid-hydrogen peroxide(5:1), and then microwave digestion-inductively coupled plasma mass spectrometry(ICP-MS) was used to determine the mass concentration of 5 metal elements. ⁷²Ge, ¹¹⁵In, ²⁰⁹Bi were used as internal standards. RESULTS The correlation coefficient of the standard curves of 5 elements was >0.999 2, detection limits were in the range of 0.001-0.055 ng·mL^-1, recoveries were in the range of 85.67%-114.14% and RSDs were in the range of 1.12%-4.26%. CONCLUSION The method is specific, accurate and sensitive, and suitable for the content determination of 5 common metal elements in Huafeng Dan.