白及胶的制剂学研究进展

Research Progress on Dosage Forms of Bletilla Striata Gum

关键词:  白及  白及胶  白及多糖  剂型  药辅合一

Key words:  Bletilla striata  Bletilla striata gum  Bletilla striata polysaccharide  dosage forms  unification of medicines and excipients

摘要:

目的 为白及胶剂型的进一步开发提供参考。方法 参阅近年来白及胶的相关剂型研究文献，归纳总结了白及胶的制剂学研究进展。结果 作为主药，白及胶可被制成乳膏剂、涂膜剂、散剂、柔性脂质体和片剂。作为药用辅料，白及胶可作为凝胶基质、成膜材料、胃漂浮缓释片辅料、难溶性药物载体和包合材料。同时作为药物和辅料，白及胶可被制成洗剂、膜剂、凝胶剂、口腔黏附片、缓释胶囊剂、滴眼剂、微球和生物可降解微针。结论 白及胶具有“药辅合一”的特性，白及胶的剂型研发具有广阔的前景。

Abstract:

OBJECTIVE To provide reference for further development of Bletilla striata gum on dosage forms. METHODS The paper summarized and reviewed the research progress on pharmaceutics of Bletilla striata gum via consulting the recent literature related to the dosage forms of Bletilla striata gum. RESULTS As the main medicine, Bletilla striata gum could be made into cream, paints, powder, flexible liposomes and tablets. As pharmaceutical excipients, Bletilla striata gum was eligible for gel base, film-forming materials, gastric-floating sustained release tablets excipients, poorly-soluble drug delivery carrier and inclusion materials. Both as the main medicine and excipients, Bletilla striata gum could be made into lotion, films, gels, buccal adhensive tablets, sustain-release capsules, eye drops, microspheres and biodegradable microneedles. CONCLUSION Bletilla striata gum is the unification of medicines and excipients. Bletilla striata gum has a broad application prospect.