ICP-MS测定衢枳壳中26种无机元素

Determination of 26 Kinds of Inorganic Elements in Qu Aurantii Fructus by ICP-MS

关键词:  衢枳壳  电感耦合等离子体质谱法  微波消解  无机元素

Key words:  Qu Aurantii Fructus  ICP-MS  microwave digestion  inorganic elements

摘要:

目的 建立微波消解-电感耦合等离子体质谱（ICP-MS）测定衢枳壳中26种无机元素（Mg、K、Ca、Na、Al、V、Cr、Mn、Fe、Co、Ni、Cu、Zn、Ga、As、Se、Rb、Sr、Ag、Cd、Cs、Ba、Tl、Pb、U、Hg）的方法。方法 样品经微波消解后，采用ICP-MS测定26种无机元素，并进行方法学验证。结果 检测的26种元素线性关系良好（r ≥ 0.999 0），平均回收率为90%~111%，RSD均<5%，精密度、重复性和稳定性试验的RSD均符合定量分析要求，检出限为0.000 7~7.226 4 μg·L^-1，测定的6批样品中Mg、K、Ca、Na、Al、Mn、Fe、Cu、Zn、Rb、Sr、Ba含量较高，V、Cr、Co、Ni、Ga、As、Cd、Cs、Tl、Pb、Hg、Se、Ag、U含量较低或未检出。结论 该方法准确、快速、灵敏，适用于衢枳壳中多种无机元素的同时测定。

Abstract:

OBJECTIVE To establish an ICP-MS method for the determination of the amounts of inorganic elements(Mg, K, Ca, Na, Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, As, Se, Rb, Sr, Ag, Cd, Cs, Ba, Tl, Pb, U, Hg) in Qu Aurantii Fructus. METHODS After the microwave digestion, 26 kinds of inorganic elements in the samples were determined by ICP-MS, and the methodology was investigated. RESULTS The 26 kinds of inorganic elements showed the good linearity in the selected concentration ranges (r ≥ 0.999 0), with the average recovery were 90%-111%, while their RSDs were< 5%. The RSD of the precision, repeatability and stability all met the demands of quantitative analysis. The detection limits were in the range of 0.000 7-7.226 4 μg·L^-1. The contents of Mg, K, Ca, Na, Al, Mn, Fe, Cu, Zn, Rb, Sr, Ba were higher in the six batchs of samples, and V, Cr, Co, Ni, Ga, As, Cd, Cs, Tl, Pb, Hg, Se, Ag, U were lower or not detected. CONCLUSION This method is accurate, rapid and sensitive, and can satisfy the simultaneous determination of elements in Qu Aurantii Fructus.