| 引用本文: | 彭德乾,王灿红,刘洋洋,魏建和.沉香的化学成分及其药理活性的研究进展[J].中国现代应用药学,2021,38(3):358-365. |
| PENG Deqian,WANG Canhong,LIU Yangyang,WEI Jianhe.Research Progress on the Chemical Constituents of Aquilariae Lignum Resinatum and Their Pharmacological Activities[J].Chin J Mod Appl Pharm(中国现代应用药学),2021,38(3):358-365. |
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| 沉香的化学成分及其药理活性的研究进展 |
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彭德乾1,2, 王灿红1,3, 刘洋洋1,3,4, 魏建和1,3,4
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1.中国医学科学院药用植物研究所海南分所, 海口 570311;2.海南医学院药 学院, 海口 571199;3.海南省南药资源保护与开发重点实验室, 海口 570311;4.中国医学科学院药用植物研究所&北京协和医学院濒危药材繁 育国家工程实验室, 北京 100193)
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| 摘要: |
| 沉香是瑞香科植物白木香Aquilaria sinensis（Lour.） Gilg含有树脂的高价值木材，广泛用于熏香、香水和药品。本文综述沉香的化学成分及药理作用研究进展，其化学成分包括单萜、倍半萜、二萜、三萜、甾醇、黄酮、苄基丙酮、色酮、酚酸和脂肪族化合物；其药理活性为抗菌、抗肿瘤和抑制乙酰胆碱酯酶等作用，为沉香后续开发提供参考。 |
| 关键词: 沉香 化学成分 药理活性 倍半萜 色酮 |
| DOI：10.13748/j.cnki.issn1007-7693.2021.03.019 |
| 分类号:R965.1 |
| 基金项目:国家重点研发计划项目（2018YEC1706401）；中国医学科学院医学与健康科技创新工程项目（2016-I2M-2-003） |
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| Research Progress on the Chemical Constituents of Aquilariae Lignum Resinatum and Their Pharmacological Activities |
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PENG Deqian1,2, WANG Canhong1,3, LIU Yangyang1,3,4, WEI Jianhe1,3,4
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1.Hainan Branch Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Haikou 570311, China;2.School of Pharmacy, Hainan Medical College, Haikou 571199, China;3.Key Laboratory of State Administration of Traditional Chinese Medicine for Agarwood Sustainable Utilization, Haikou 570311, China;4.National Engineering Laboratory for Breeding of Endangered Medicinal Materials and Pharmacology and Toxicology Centers, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China
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| Abstract: |
| Aquilariae Lignum Resinatum formed in the Aquilaria sinensis (Lour.) Gilg, is the highly valuable product which was commonly used for incenses, perfumes and medicines. In this paper, chemical composition and pharmacological activity of Aquilariae Lignum Resinatum were reviewed. Its chemical composition included monoterpenes, sesquiterpenes, diterpenoids, triterpenes, steroids, flavonoids, benzyl acetones, chromones, phenolic acids and aliphatic compounds. Its pharmacological activity included anti-bacterial, anti-tumor and acetylcholinesterase inhibitive effects, etc. This will provide a reference for further development of the agarwood. |
| Key words: Aquilariae Lignum Resinatum chemical constituent pharmacological activity sesquiterpene chromone |
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