| 引用本文: | 余琰,郭玫,王丽娟.六味调更片的定性定量研究[J].中国现代应用药学,2020,37(12):1468-1473. |
| YU Yan,GUO Mei,WANG Lijuan.Qualitative and Quantitative Study of Liuwei Tiaogeng Tablets[J].Chin J Mod Appl Pharm(中国现代应用药学),2020,37(12):1468-1473. |
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| 六味调更片的定性定量研究 |
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余琰1,2, 郭玫1,2, 王丽娟2,3
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1.甘肃中医药大学, 兰州 730101;2.甘肃省高校中(藏)药化学与质量研究省级重点实验室, 兰州 730101;3.甘肃省中药质量与标准研究重点实验室, 兰州 730101
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| 摘要: |
| 目的 建立六味调更片的定性定量测定方法，为其质量控制提供依据。方法 采用薄层色谱法对六味调更片中女贞子、枸杞子、当归、黄芪进行定性鉴别；采用HPLC对六味调更片中黄芪甲苷、阿魏酸进行含量测定。结果 薄层色谱鉴别项斑点清晰，分离度好，阴性无干扰；含量测定项各成分线性关系均良好，平均回收率均符合要求。结论 建立的定性定量方法简便，结果准确，可用于六味调更片的质量控制。 |
| 关键词: 六味调更片 质量控制 薄层色谱法 高效液相色谱法 |
| DOI：10.13748/j.cnki.issn1007-7693.2020.12.012 |
| 分类号:R917.101 |
| 基金项目:2018年甘肃省中医药管理局科研课题（GZK-2018-7）；甘肃省高校中（藏）药化学与质量研究省级重点实验室开放基金（ZZY-2016-03）；2017年度甘肃省中药质量与标准研究重点实验室培育基地开放基金（ZYZL17-001） |
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| Qualitative and Quantitative Study of Liuwei Tiaogeng Tablets |
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YU Yan1,2, GUO Mei1,2, WANG Lijuan2,3
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1.Gansu University of Chinese Medicine, Lanzhou 730101, China;2.Key Laboratory of Chemistry and Quality for Traditional Chinese Medicines of the University of Gansu Province, Lanzhou 730101, China;3.Key Laboratory of TCM Quality and Standard of Gansu Province, Lanzhou 730101, China
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| Abstract: |
| OBJECTIVE To establish the qualitative and quantitative methods for the quality control of Liuwei Tiaogeng tablets. METHODS Ligustri Lucidi Fructus, Lycii Fructus, Angelicae Sinensis Radix, Angelicae Sinensis Radix were identified by TLC, and the contents of astragaloside IV and ferulic acid were determined by HPLC. RESULTS The spots in TLC were clear with good separation and the blank tests showed no interference. Each component showed good linear relationship in quantitative tests and the average recoveries met the requirements. CONCLUSION The proposed qualitative and quantitative methods are simple and accurate, and can be used for quality control of Liuwei Tiaogeng tablets. |
| Key words: Liuwei Tiaogeng tablets quality control TLC HPLC |
