化疗药物合理使用评价体系的构建和实施

Establishment and Practice of the Evaluation System for Rational Use of Chemotherapeutic Drugs

关键词:  化疗药物  合理使用  评价标准

Key words:  chemotherapeutic drugs  rational use  evaluation criteria

摘要:

目的 构建科学化、系统化的肿瘤化疗药物合理使用评价体系。方法 建立医院肿瘤化学药物治疗管理工作组，由资深临床医师、药师等共同制定化疗药物临床使用规范和点评标准。临床药师根据建立的点评标准对化疗病历进行点评。结果 药师点评突破了以往仅局限于化疗药物适应证、用法用量、预处理等初级模式，从化疗前基本要求、化疗方案评估和化疗后不良反应处理各个环节发现了问题并进行了全方位点评。结论 建立的化疗药物合理使用评价体系在点评指标方面更加全面细化，适用于临床。

Abstract:

OBJECTIVE To establish a scientific and systematic evaluation system for the rational use of cancer chemotherapeutic drugs. METHODS The management team of cancer chemotherapeutic drugs in hospital was established. Senior clinicians and pharmacists jointly drafted the criteria for clinical use and evaluation method of chemotherapeutic drugs. Clinical pharmacists commented on the case history of chemotherapy according to the established evaluation criteria. RESULTS Pharmacist's comment broke through the primary mode which was limited to the indication, usage, dosage and pretreatment of chemotherapeutic drugs in the past, and found out the problems from the basic requirements before chemotherapy, the evaluation of chemotherapeutic schemes and the treatment of adverse reactions after chemotherapy. CONCLUSION The evaluation system of rational use of chemotherapeutic drugs established is more comprehensive and detailed in the evaluation indicators, which is suitable for clinical use.