基于数据挖掘的中医治疗黄褐斑用药规律分析

Analysis on the Rule of Traditional Chinese Medicine in Treating Chloasma Based on Data Mining

关键词:  中药  黄褐斑  用药规律  中药面膜

Key words:  traditional Chinese medicine  chloasma  medication rule  traditional Chinese medicine mask

摘要:

基于数据挖掘对中医治疗黄褐斑的用药规律及特点进行分析。方法 以“黄褐斑”和“中药”为关键词，搜索中国知网近10年相关文献，对临床上治愈率达70%的治疗黄褐斑的方剂进行整理，并对文献中的治疗方法、高频药物、药物配伍、用药剂量、疗程等进行归纳分析。结果 共筛选出治疗黄褐斑的方剂277首，其中内服方剂173首、外用方剂104首；用药方式中使用频次较高的为中药内服（31.28%），其次是内服联合面膜外用（23.08%）；在药物统计分析中，内服方剂用药频次较高的前3味中药是当归、茯苓和川芎；中药外敷方剂中，用药频次较高的前3味中药是白芷、茯苓和白及。药物剂量、疗程、不良反应均因病因、用药以及个人体质的不同而有所差异。结论 中医治疗黄褐斑时，以内服和面膜外敷联合治疗效果更佳，多选择活血化瘀药和补血药调节机体，合并中药面膜外敷、针灸、围刺等治疗方式同时治疗，并取得了很好的疗效，从而达到标本兼治的目的。

Abstract:

OBJECTIVE To analyze the regularity and characteristics of traditional Chinese medicine in the treatment of chloasma based on data mining. METHODS Based on the key words of "chloasma" and "traditional Chinese medicine", the relevant literatures of CNKI in the past decade were searched, the prescriptions for chloasma with a clinical cure rate of 70% were sorted out, and the treatment methods, high-frequency drugs, drug compatibility, dosage and treatment course in the literatures were summarized and analyzed. RESULTS A total of 277 prescriptions for chloasma were selected, including 173 prescriptions for internal use and 104 prescriptions for external use; the most frequently used drugs were traditional Chinese medicine for internal use(31.28%), followed by combination of internal and external application of mask(23.08%); in the statistical analysis of drugs, the top three traditional Chinese medicines with the highest frequency for internal use were Angelicae Sinensis Radix, Poria cocos and Chuanxiong Rhizoma; In the prescription of external application of traditional Chinese medicine, the three most frequently used drugs were Angelicae Dahuricae Radix, Poria cocos and Bletilla striata. Drug dosage, course of treatment and adverse reactions were different due to different etiology, medication and individual constitution. CONCLUSION When treating chloasma with traditional Chinese medicine, it is better to treat chloasma with the combination of internal administration and external application of mask. It is better to choose blood activating stasis removing drugs and blood enriching drugs to regulate the body, and combine traditional Chinese medicine facial mask external application, acupuncture and surrounding needling at the same time, and achieve a good effect, so as to achieve the purpose of both manifestation and root cause of disease.