181例药源性肺水肿文献分析

Literature Analysis of 181 Cases of Drug-induced Pulmonary Edemas

关键词:  药品不良反应  肺水肿  文献分析

Key words:  adverse drug reaction  pulmonary edema  literature analysis

摘要:

目的 探讨药物引起肺水肿的特点及一般规律。方法 检索《中国医院数字图书馆》，对1990年1月—2010年4月国内医药学术期刊报道的药物引起肺水肿181例进行统计、分析。结果 药物引起肺水肿的给药途径为口服给药、肌肉注射、静脉给药等；引起肺水肿的药物种类以抗精神病药、利尿脱水药较多。结论 临床应重视药物引起的肺水肿。

Abstract:

OBJECTIVE To discuss the characteristics and general pattern of drug-induced pulmonary edemas. METHODS A total of 181 drug-induced pulmonary edema cases reported in internal medical journals published from January 1990 to April 2010 were collected by retrieving China Hospital Digital Library and analyzed statistically. RESULTS Leading the routes of administration inducing pulmonary edemas were oral administration, intramuscular injection, intravenous administration, and so on. The pulmonary edemas were predominantly caused by anti-psychotic drug and dehydration drugs. CONCLUSION Clinic should attach great importance to drugs-induced pulmonary edemas.