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| 摘要: |
| 用溶媒法制备了利福定固体分散物。经X—射线衍射实验证明,利福定在固体分散物中呈无定形或以分子状态分散于载体中。固体分散物2小时的体外溶出量和人体生物利用度分别较原药提高了88%和21.8%。 |
| 关键词: 利福定 固体分散物 生物利用度 |
| DOI： |
| 分类号: |
| 基金项目: |
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| The Preparation and Determination of Bioavailability of Rifandin Solid Dispersion |
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He Zhonggui Tang xing Cai Yumin
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| Abstract: |
| Rifandin Solid Dispersion (RSD) were prepared by using "solvent method". Result showed that Rifandin (R) was dispersed in carrier with amorphous or molecularity through x-ray diffract experiment. The disolution amount of R in RSD was 88% more than that of |
| Key words: Rifandin Solid dispersion Bioavailability |
