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| 摘要: |
| 应用荧光探针DPH测定完整红细胞膜流动性。山茛菪碱显著增加红细胞膜流动性。山茛菪碱对红细胞膜内源荧光的焠灭呈药物浓度依赖,钙和山茛菪碱对红细胞膜内源荧光的焠灭有协同作用,提示山茛菪碱对膜疏水区有作用,并且直接与膜蛋白反应导致能量转移。 |
| 关键词: 山莨菪碱 红细胞膜 膜流动性 钙 |
| DOI： |
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| Effect of Anisodamine on the fluidity of erythroyte membrane and the intrinsic fluorescence of ghost |
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Yan Goudong Zhou Wenhua,et al.
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| Abstract: |
| Anisodamine(Ani)could increase significantly the intact erythrocyte membrane fluidityin the presence or absence of CaCl2.The intrinsic fluorecence of erythrocyte ghost was depressedby Ani in a dose-dependent manner.In the presence of 2 mmol/L CaCl2 and An |
| Key words: Auisodamine Erythrocyte membrane membrane fluidity Calcium |
