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| 摘要: |
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| 关键词: ONO-1078 甲哟酮 氢化可的松 微血管渗漏性 气道阻力 |
| DOI: |
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| Effects of Drugs on Antigen-induced Bronchoconstrictor and AirwayMicrovascular Leakage in Sensitized Guinea Pigs |
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Wei Erqin Sun Shuhua
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| Abstract: |
| In actively sensitized guinea pigs, ONO-1078, a potent spesific antagonist forleukotrienes, inhibited the antigen-induced microvascular leakage in the bronchi, lungs andbrochoconstrictor response. Metyrapone poteatiated these responses, while hydrocortiso |
| Key words: ONO-1078 Metyrapone Hydrocortisone Microvascular leakage Bronchoconstriction (on page 9 ) |