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| 摘要: |
| 以α-吡咯烷酮和氯乙酸甲酯为原料,经缩合、氨解反应合成吡乙酰胺。并应用正交设计和均匀设计试验优化反应条件,总收率达66%。 |
| 关键词: 吡乙酰胺 正交设计 均匀设计 |
| DOI： |
| 分类号: |
| 基金项目: |
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| Improved Process of Synthesis on Pyracetam |
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Wang Li-chen et al
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| Abstract: |
| 2-pyrolidone and methyl chlotoacetate were used as starting materials via twosteps: condensation and ammonolysis to yield pyracetam. The total yield of pyracetam is 66%.Orthogonal design and Uniform design were used in the synthesis. |
| Key words: Pyracetam Orthogonal design Uniform design |
