| 引用本文: | 赵鲁杭;孙红颖;郑妮娜;李菊花;姚彤炜;陈枢青.细胞色素P450 2C19单碱基突变位点CYP2C19m1的分析[J].中国现代应用药学,1998,(3):36-38. |
| Zhao Luhang(Zhao LH),Sun Hongying(Su HY),Zheng Nina(Zheng NN),et al.Analysis of single base mutation of cytochrome P450 2C19 allele CYP2C19m1[J].Chin J Mod Appl Pharm(中国现代应用药学),1998,(3):36-38. |
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| 摘要: |
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| 关键词: 细胞色素P4502C19(CYP2C19) CYP2C19ml 基因分型 等位基因特异扩增法(ASA) |
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| 基金项目:浙江省自然科学基金资助课题第396473号 |
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| Analysis of single base mutation of cytochrome P450 2C19 allele CYP2C19m1 |
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Zhao Luhang(Zhao LH),Sun Hongying(Su HY),Zheng Nina(Zheng NN),et al
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| Abstract: |
| OBJECTIVE: Cytochrome P450 2C19 enzyme deficiency was mainly caused by CYP2C19ml allele.It was said more than 83 % of poor metabolizers were due to the existence of this allele. This study was aimed to set up an efficient PCR procedure to analyse this all |
| Key words: Cytochrome P450 2C19(CYP2C19) CYP2C19ml Genotyping Allele - specific amplification |
