| 引用本文: | 王仁定;张纬萍;王苹丽;曾玲晖;魏尔清.白三烯拮抗剂ONO-1078对小鼠持续性局灶性脑缺血的作用[J].中国现代应用药学,2001,(6):431-433. |
| Wang Rending (Wang RD), Zhang Weiping (Zhang WP),Wang Pingli (Wang PL), et al.Effect of ONO-1078, a leukotriene antagonist, on permanent focal cerebral ischemia in mice[J].Chin J Mod Appl Pharm(中国现代应用药学),2001,(6):431-433. |
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| 摘要: |
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| 关键词: 4-氧-8-[对-(4-苯丁氧基)苯甲酰氨基]-2-(5-四唑基)-4H-1-苯并吡喃半水合物(ONO-1078) 尼莫地平 脑缺血 脑梗死 脑水肿 |
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| 基金项目:国家自然科学基金项目 (No.39770270)资助 |
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| Effect of ONO-1078, a leukotriene antagonist, on permanent focal cerebral ischemia in mice |
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Wang Rending (Wang RD), Zhang Weiping (Zhang WP),Wang Pingli (Wang PL), et al
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| Abstract: |
| OBJECTIVE:To determine whether ONO-1078{ 4-oxo-8-[p-(4-phenylbntyloxy)benzoyl-amino]-2-(tetrazd-5-yl)-4H-1-benzopyran hemihydrate},a potent leukotriene antagonist, has a protective effect on focal cerebral ischemia in a mouse model. METHOD:Focal cerebral |
| Key words: 4-oxo-8-[p-(4-phenylbutyloxy) benzoyl amino]-2-(tetrazd-5-yl)-4H-1-benzopyran hemihydrate (ONO-1078, pranlukast), nimodipine cerebral ischemia, cerebral infarction brain edema |
