|
| 摘要: |
|
| 关键词: 甲苯咪唑 微丸 固体分散体 均匀设计 溶出度 |
| DOI： |
| 分类号: |
| 基金项目:新疆维吾尔自治区卫生厅医学科学研究基金资助项目 |
|
| Optimization of preparation process of mebendazole pellets by uniform design |
|
Li Yan,Sun Dian Jia
|
| Abstract: |
| OBJECTIVE:A new preparation was studied to prepare mebendazole (MBZ) pellets by spherinization of solid dispersion in order to increase the dissolution and bioavalability of MBZ which was a poorly water soluble drug.METHOD:Uniform design was used in the |
| Key words: Mebendazole,Pellets,Solid dispersion,Uniform design,Dissolution |
