| 引用本文: | 欧志敏1*,吴坚平2,杨立荣2,岑沛霖2.水/有机相两相体系中Saccharomyces cerevisiae B5不对称还原制备手性药物中间体R-2'-氯-1-苯乙醇的研究[J].中国现代应用药学,2004,(8):40-42. |
| Ou Zhi-min1， Wu Jian-ping2， Yang Li-rong2，Cen Pei-lin2.Preparation of chiral pharmaceutical intermediate R-2'-chloro-1-phenyl-ethanol with the method of Saccharomyces cerevisiae B5 asymmetric reduction in water/organic diphasic system[J].Chin J Mod Appl Pharm(中国现代应用药学),2004,(8):40-42. |
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| 关键词: 水/有机相两相体系 Saccharomyces cerevisiae B5 不对称还原 手性药物中间体 R-2'-氯-1-苯乙醇 |
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| Preparation of chiral pharmaceutical intermediate R-2'-chloro-1-phenyl-ethanol with the method of Saccharomyces cerevisiae B5 asymmetric reduction in water/organic diphasic system |
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Ou Zhi-min1， Wu Jian-ping2， Yang Li-rong2，Cen Pei-lin2
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| Abstract: |
| The process of preparation of chiral pharmaceutical intermediate R-2'-chloro-1-phenyl-ethanol with the method of Saccharomyces cerevisiae B5 asymmetric reduction in water/organic diphasic system was investigated in detail. The result shows that the higher |
| Key words: water/organic diphasic system Saccharomyces cerevisiae B5 asymmetric reduction chiral pharmaceutical intermediate R-2'-chloro-1-phenyl-ethanol |
