| 引用本文: | 张灿;丁娅;平其能.半乳糖化季铵壳聚糖衍生物的设计、合成和表征[J].中国现代应用药学,2005,(5):386-388. |
| ZHANG Can,DING Ya,PING Qi-neng.Design,synthesis and characterization of N-trimethyl chitosan derivatives having pendant galactose residues[J].Chin J Mod Appl Pharm(中国现代应用药学),2005,(5):386-388. |
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| 摘要: |
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| 关键词: 壳聚糖 季铵 半乳糖基 肝靶向 基因载体 |
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| 基金项目:国家自然科学基金项目(30271554);;教育部科技研究重点项目基金(03090)资助 |
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| Design,synthesis and characterization of N-trimethyl chitosan derivatives having pendant galactose residues |
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ZHANG Can,DING Ya,PING Qi-neng
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| Abstract: |
| OBJECTIVE To synthesize and characterize N-trimethyl chitosan derivatives having pendant galactose residues for potential gene delivery carriers for hepatocyte-targeting.METHOD Firstly,a water-soluble N-trimethyl chitosan derivatives(TMCS) was prepared.To |
| Key words: chitosan galactose group hepatocyte-targeting gene carrier |
