| 引用本文: | 符芳芳，陈功星，张家炜，郑树，丁佳逸.针对PLK1基因mRNA的SiRNA治疗结肠癌的细胞学研究[J].中国现代应用药学,2005,(8):699-701. |
| FU Fang-fang, CHEN Gong-xing, ZHANG Jia-wei, ZHENG Shu, DING Jia-yi.Cytological study about SiRNA to PLK1 mRNA on colorectal cancer therapy[J].Chin J Mod Appl Pharm(中国现代应用药学),2005,(8):699-701. |
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| 摘要: |
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| 关键词: SiRNA PLK1 细胞存活 细胞凋亡 |
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| 基金项目:国家自然科学基金资助(30471943) |
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| Cytological study about SiRNA to PLK1 mRNA on colorectal cancer therapy |
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FU Fang-fang, CHEN Gong-xing, ZHANG Jia-wei, ZHENG Shu, DING Jia-yi
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| Abstract: |
| OBJECTIVETo study the survival and growth of colorectal cell line SW480 treated by small interfering RNA (SiRNA) that aims to PLK1 (Polo-like kinase 1) mRNA. METHODSThree chemically synthesized SiRNA molecules were designed targeting different sites of PL |
| Key words: SiRNA PLK1 cell survival apoptosis |
