| 引用本文: | 高缘1;张建军2;樊伟明3;任秉钧3.氯诺昔康注射剂的研制——处方前溶解度研究[J].中国现代应用药学,2006,(3):207-209. |
| GAO Yuan~(1),ZHANG Jian-jun~(2),FAN Wei-ming~(3),REN Bing-jun~(3).Study on the preparation of Iorhoxicam injection——Solubilization of lornoxicam[J].Chin J Mod Appl Pharm(中国现代应用药学),2006,(3):207-209. |
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| 摘要: |
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| 关键词: 氯诺昔康 溶解度 潜溶 胶束形成 络合 |
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| Study on the preparation of Iorhoxicam injection——Solubilization of lornoxicam |
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GAO Yuan~(1),ZHANG Jian-jun~(2),FAN Wei-ming~(3),REN Bing-jun~(3)
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| Abstract: |
| OBJECTIVE To study the solubility of lornoxicam,a waterinsoluble non-steroidal anti-inflammatory drug,for the purpose of the preparation of its parenteral injection.METHODS Solubility determination was performed by HPLC method.The effect of pH control,cos |
| Key words: lornoxicam solubility cosolvency micellization complexation |
