| 引用本文: | 王俏1;蒋晓航2;姜毓丽1;陈国神1.石杉碱甲的大鼠鼻黏膜吸收研究[J].中国现代应用药学,2007,(2):94-96. |
| WANG Qiao1,JIANG Xiao-hang2,JIANG Yu-li1,CHEN Guo-shen1.Study on Nasal Mucosa Absorption of Huperzine A in Rats[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(2):94-96. |
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| 关键词: 石杉碱甲 鼻腔循环灌流 鼻黏膜吸收 吸收速度常数 |
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| Study on Nasal Mucosa Absorption of Huperzine A in Rats |
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WANG Qiao1,JIANG Xiao-hang2,JIANG Yu-li1,CHEN Guo-shen1
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| Abstract: |
| OBJECTIVE To investigate the nasal absorption of huperzine A,which is a reversible acetylcholinesterase inhibitor for the treatment of Alzheimer's disease.METHODS In situ nasal recirculation method was used to estimate the nasal absorption rate constants |
| Key words: huperzine A in situ rat nasal recirculation test nasal absorption absorption rate constant |