| 引用本文: | 夏春华1;王晓华2;熊玉卿1;章新晶1.高效液相-质谱法测定人体血浆中吲哒帕胺的浓度及其生物等效性研究[J].中国现代应用药学,2007,(2):136-138. |
| XIA Chun-hua1,WANG Xiao-hua2,XIONG Yu-qing1,ZHANG Xin-jing1.Determination of Indapamide in Human Plasma by HPLC-MS and Study on its Pharmacokinetics[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(2):136-138. |
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| 摘要: |
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| 关键词: 吲哒帕胺 高效液相-质谱 生物等效性 |
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| Determination of Indapamide in Human Plasma by HPLC-MS and Study on its Pharmacokinetics |
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XIA Chun-hua1,WANG Xiao-hua2,XIONG Yu-qing1,ZHANG Xin-jing1
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| Abstract: |
| OBJECTIVE To develop an HPLC-MS assay for determination of indapamide in human plasma and to evaluate the bioavailability in healthy volunteers.METHODS Plasma was extracted with diethyl ether and separated by a C18 column with a mobile phase of methanol-w |
| Key words: indapamide HPLC-MS bioavailability |
