| 引用本文: | 葛海霞1;王礼琛2;倪生良1.抗精神病药阿立哌唑的合成工艺改进[J].中国现代应用药学,2007,(4):294-295. |
| GE Hai-xia1,WANG Li-chen2,NI Sheng-liang1.Improved Synthesis of Antipsychotic Drug Aripiprazole[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(4):294-295. |
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| 关键词: 阿立哌唑 合成 工艺改进 抗精神病药 |
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| Improved Synthesis of Antipsychotic Drug Aripiprazole |
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GE Hai-xia1,WANG Li-chen2,NI Sheng-liang1
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| Abstract: |
| OBJECTIVE To improve the synthetic procedure of antipsychotic drug aripip-razole.METHODS Aripiprazole was synthesized via four steps starting from m-Anisidine. RESULTS Aripiprazole was prepared in an overall yield of 40%.The structure of the target compou |
| Key words: aripiprazole synthesis process improvement antipsychotic |
