| 引用本文: | 郑国钢1,2;李会林2;申屠建中3;曾苏1.LC-MS法测定人血浆中雷米普利及其活性代谢产物雷米普利拉的浓度[J].中国现代应用药学,2007,(4):310-313. |
| ZHENG Guo-gang1,2,LI Hui-lin2,SHENTU Jian-zhong3,ZENG Su1.Determination of Ramipril and Its Active Metabolite Pamiprilat in Human Plasma by LC-MS[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(4):310-313. |
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| 关键词: 雷米普利 雷米普利拉 液相色谱-质谱联用法 血浆药物浓度 |
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| Determination of Ramipril and Its Active Metabolite Pamiprilat in Human Plasma by LC-MS |
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ZHENG Guo-gang1,2,LI Hui-lin2,SHENTU Jian-zhong3,ZENG Su1
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| Abstract: |
| OBJECTIVE To establish a LC-MS-MS method for the determination of ramiprilat and its active metabolite ramiprilat in the human plasma.METHODS Enalapril was used as the internal standard.Ramipril and Ramiprilat was chromatographed by using a Waters Atlanti |
| Key words: ramipril ramiprilat LC-MS-MS plasma concentration |
